Proteome Sciences R&D GmbH & Co KG

Proteome Sciences is a life sciences company delivering content for personalised medicine through three areas:

* Services
* Biomarkers
* Reagents

with a strong track record in discovery, innovation and intellectual property (IP).

Proteome Sciences, a global leader in applied proteomics, uses high sensitivity proprietary technologies to detect biomarkers (differentially expressed proteins in diseases) and to develop rapid assays for testing. The biomarkers discovered in body fluids or tissues are validated, developed and commercialised as diagnostic, prognostic or therapeutic products through strategic alliances and out-licensing.

PS Biomarker Services™ – A modular biomarker outsourcing solution to the pharmaceutical, biotechnology and diagnostics industries

Separate modules for discovery, validation and routine measurement of biomarkers are based around proprietary isobaric and isotopic Tandem Mass Tags® (TMT®) and both gel-based and gel-free separation technologies linked to state-of-the-art mass spectrometry. This significantly increases the speed, robustness and precision of biomarker discovery/quantification and facilitates the rapid transition to multiplex biomarker assays for routine application.

Biomarkers – A broad selection of proprietary protein biomarkers across a range of key human diseases

Proteome Sciences has established a comprehensive intellectual property portfolio covering markers in CNS disorders (Alzheimer’s, stroke, traumatic brain injury, TSE’s & pain), Oncology (lung, breast, esophageal, colorectal cancers & neuroblastoma) and organ transplant rejection (renal, cardiac).

Reagents – Proteome Sciences’ patented isobaric mass tag technology

Proteome Sciences has developed a range of novel isobaric and isotopic reagents under the Tandem Mass Tag® brand which are licensed and distributed worldwide by Thermo Scientific. TMT® works like a car tracker system to uniquely tag proteins and peptides, radically reducing the variability of biomarker discovery and speeding up the transition to biomarker validation. Proteome Sciences controls the global isobaric mass tag space through issued US and European TMT® patents.

Proteome Sciences has state-of-the-art research facilities in London, UK and ISO 9001:2008 accredited facilities in Frankfurt, Germany. These are complemented through a range of collaborations with leading academic research establishments worldwide.

All aspects of biomarker services, custom tagging, assay development and proteomics workflows can be outsourced from PS Biomarker Services.