University Hospital Bonn Institute of Clinical Chemistry and Clinical Pharmacology

The Institute of Clinical Chemistry and Clinical Pharmacology represents the two areas of Clinical Chemistry and Clinical Pharmacology in research, teaching, and healthcare. It includes the Central Laboratory of the University Hospital, a Phase I unit for early clinical trials, and numerous research groups. The institute is member of the Cluster of Excellence ImmunoSensation, the Center for Integrated Oncology (CIO) Cologne Bonn, and the German Center for Infection Research (DZIF). 

In the Liedmann lab our research is focused on generation-spanning immune regulation. How does the environment influence the epigenetic landscape of our germ cells? How are changes to the epigenetic landscape transmitted through generations? And how does that shape the immunity of our children and grandchildren? Questions like these are driving our work. To answer those questions, we utilize human and mouse germ cells, in vivo model systems, and state of the art sequencing technologies.