PhD Position

The advertised position is located at the Department for Radiotherapy (principle investigator(s): Prof. Dr. Martin Stuschke. The project is linked to the focus area Lung Cancer of the GRK.

The PhD project of Prof. Stuschke and Dr. Sak will study the effect of epigenetic modulation of chromatin on the sensitivity of lung cancer cell lines to cisplatin or irradiation as defined in the project. The role of miRNAs with reported function in regulating key chromatin remodellers and their effect on the DNA damage response and radiosensitivity in a panel of molecularly defined cell lines representing clinically relevant NSCLC subtypes.
The GRK 2762 on “Heterogeneity, plasticity and dynamic in cancer cell, tumor and normal tissue responses to cancer radiotherapy” offers outstanding internationally-oriented interdisciplinary scientific research and training opportunities for graduates of experimental or computational life sciences and (bio)medicine with interest in basic and translational cancer research and computational biology (http://www.uni-due.de/med/forschung/grk2762/index.shtml)

Qualification profile

• Talented and enthusiastic candidates with high interest in the research topic of GRK 2762
• Strong Diploma/Master degree in Cell or Molecular Biology, Biochemistry, Radiation Biology, Experimental Diploma/Master degree Medicine, Computational Biology or related fields
• High motivation and commitment for active cross-disciplinary collaboration
• Abilities for problem-solving and independent work
• Work with laboratory animals may be obligatory (depending on the project)
• Fluent in spoken and written English (knowledge of German is not a requirement)

We offer

• Opportunity to conduct high-level interdisciplinary research projects
• Stimulating interdisciplinary and internationally-oriented academic environment
• Innovative cross-disciplinary scientific training for PhD and MD students at the interface between radiation biology and oncology, precision medicine, and computational biology
• Training in transferable academic and soft skills
• Funding for active participation in workshops and conferences and international visits to collaboration partners
• Regular supervision and mentoring
• Excellent career opportunities