Headerbild Klinikum der Johann Wolfgang Goethe-Universität

The Institute for Vascular Signalling is a research institute that studies the biology of the vascular wall, heart and the factors that influence them during disease development. There is a particularly strong focus on the endothelial cells that are the inner most lining of the blood vessel and directly exposed to the flowing blood. We study substances generated by the endothelial cells themselves such as nitric oxide, hydrogen sulfide, mediators generated from polyunsaturated fatty acids and, more recently, microproteins. A further series of projects focus on the cardiovascular complications of diabetes in the heart as well as the impact of platelets, platelet-derived products and monocytes. All of the projects have a translational biomedicine emphasis with the aim of improving on current cardiovascular disease therapy.

Collaborative networks:
Projects housed at the Institute for Vascular Signalling belong to four different collaborative research centres (CRCs) including CRC 1531 Damage control by the stroma-vascular compartment, CRC 1039 Disease-relevant signal transduction by fatty acid derivatives and sphingolipids, CRC 1366 Vascular Control of Organ Function and CRC-TRR 267 Cardiovascular ncRNAs. The institute also belongs to the German Research Foundation funded Excellence Cluster Cardio Pulmonary Institute ( CPI) and the German Centre for Cardiovascular Research ( DZHK).

At the Institute for Vascular Signalling, Center for Molecular Medicine at the Faculty of Medicine, Goethe University, there is an open

Postdoc position (m/f/d)

(E13 TV-G-U)

to study inter- and intra-cellular metabolic communication in a DFG funded research project in the framework of collaborative research center 1531 (https://sfb1531.de). The position is available at the earliest possible date and is initially for 2 years with subsequent prolongation possible. The salary classification is based on the job characteristics of the collective agreement applicable to Goethe University (TV-G-U).

PostDoc - to study inter- and intra-cellular metabolic communication, epigenetics (m/f/d)

Activities and responsibilities

The position requires the following:

participation in a research project focusing on metabolic communication between endothelial cells and pericytes
preferred candidates would have experience in studying protein-protein interactions, post-translational modifications and epigenetic regulation mechanisms, including sequencing

Qualification profile

Requirements:

a completed, very good PhD in biochemistry, biology, biotechnology, molecular medicine or an equivalent discipline
experience in protein chemistry and the analysis of large data sets e.g. sequencing
preference will be given to applicants with expertise in metabolism and metabolomics
good self-organization and team working abilities

excellent written and spoken English is required

We offer

We offer:

a thematic high-level project in an internationally recognized group (www.ivs-frankfurt.de) which is part of the DFG Cluster of Excellence \"CardioPulmonary Institute\" (www.cpi-online.de) and the German Center for Cardiovascular Research (www.dzhk.de)

an international and inclusive environment promoting curiosity and critical thinking leading to impactful scientific discoveries
collaboration with a graduate school (https://sfb1531.de/programme) that provides the specific know-how needed to conduct cutting-edge research in cardiovascular biology, as well as mentoring for personal development

labs in a new research building, with modern facilities and analysis possibilities from integrative physiology to mass spectroscopy

Applications including a cover letter, CV, degree certificates together with the names and contact details of three referees should be submitted as one PDF in electronic form to Prof. Dr. Ingrid Fleming (email).

Jetzt bewerben

Vollzeit , Befristete Anstellung

Postdoc

Aktualisiert am 07.11.2024

Bitte beziehe dich bei deiner Bewerbung auf jobvector und verwende die folgende Referenznummer: 202411-PostDoc-SFB1531-B03