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PhD Position – RNA localization regulation and function
Institute of Cardiovascular Regeneration
Frankfurt am Main, Hessen
57.708 €/Jahr (geschätzt)
Molekularbiologie
RNA
Einzelmolekül-Bildgebung
Forschung
The Johann Wolfgang Goethe University Frankfurt is one of the largest universities in Germany with about 48,000 students and around 5,000 employees. Founded in 1914 by Frankfurt citizens and since 2008 back in the legal form of a foundation, the Goethe University has a high degree of autonomy, modernity and professional diversity. As a full-service university, the Goethe University Frankfurt offers more than 100 study programs on five campuses in a total of 16 faculties and at the same time has outstanding research strength.
Applications are invited for one
PhD position (m/f/d)
65%
(E13 TV-G-U)
65%
(E13 TV-G-U)
available at the Institute of Cardiovascular Regeneration at the Goethe-University of Frankfurt (Germany).
The contract is initially limited to 2 years with the possibility of extension.
We study the dynamic mechanisms underlying the subcellular localization regulation of coding and long non-coding RNAs in both healthy and disease states. Our interdisciplinary approach combines advanced imaging with molecular and computational techniques to explore how RNA localization influences cellular function and pathology. Our team is looking for experimental and/or computational applicants.
The contract is initially limited to 2 years with the possibility of extension.
We study the dynamic mechanisms underlying the subcellular localization regulation of coding and long non-coding RNAs in both healthy and disease states. Our interdisciplinary approach combines advanced imaging with molecular and computational techniques to explore how RNA localization influences cellular function and pathology. Our team is looking for experimental and/or computational applicants.
PhD Position – RNA localization regulation and function
Activities and responsibilities
The successful candidate will utilize targeted and multiplexed single-molecule RNA imaging methods to visualize RNA molecules at high resolution. In addition, the candidate will investigate the interactions between RNAs and proteins that regulate their localization and function. They will also employ high-throughput sequencing techniques such as RNA-seq to profile RNA populations and uncover regulatory patterns, and apply genome editing tools such as CRISPR-Cas9 to manipulate RNA regulatory motifs and assess functional outcomes. Computational skills in data analysis are highly valued.
Qualification profile
The ideal candidate will be passionate about molecular biology and eager to contribute to innovative research. A strong foundation in experimental techniques and a keen interest in RNA biology are highly desirable, background in computational biology is a plus.
We offer
Our laboratory offers a stimulating and collaborative working environment with state-of-the-art infrastructure and unique professional career development opportunities. We are a part of the CPI Cluster of Excellence, TRR267 on non-coding RNAs in the cardiovascular system, and SCALE with numerous opportunities to engage with researchers working in diverse fields. We value diversity and encourage applicants from all backgrounds to apply.
Interested candidates should send their cover letter and CV as a single PDF to Dr. Gabrijela Dumbovic (by email to email), Institute for Cardiovascular Regeneration, Center for Molecular Medicine, House 25B, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany
The University advocates equal rights for women and men and therefore strongly encourages women to apply. People with disabilities are given priority if they have the same qualifications.
Please do not submit any originals as the application documents cannot be returned. Travel and application costs cannot be reimbursed.
The University advocates equal rights for women and men and therefore strongly encourages women to apply. People with disabilities are given priority if they have the same qualifications.
Please do not submit any originals as the application documents cannot be returned. Travel and application costs cannot be reimbursed.
Teilzeit
, Befristete Anstellung
Doktorandenstelle
Aktualisiert am
27.03.2025
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Gehalt
Der angegebene Wert ist das geschätzte durchschnittliche Bruttojahresgehalt für vergleichbare Vollzeitpositionen.
€ 57.708
Arbeitsort
Standort der Stelle
Theodor-Stern-Kai 7
60431 Frankfurt am Main
Hessen
Deutschland
Gut zu erreichen aus...
- Wiesbaden
- Mainz
- Darmstadt
- Offenbach am Main
- Hanau
- Gießen
Über Institute of Cardiovascular Regeneration
Main focus of our Institute is the research and development of potential therapeutics for the treatment of cardiovascular diseases. The Institute elucidates the basic mechanisms underlying cardiovascular disease and vessel growth with the aim to develop new cellular and pharmacological therapies for improving the treatment of cardiovascular disease. Ongoing research focuses on epigenetic...
Mehr über Institute of Cardiovascular Regeneration