Headerbild Deutsches Krebsforschungszentrum (DKFZ)

„Research for a life without cancer“ is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts - whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The Division of Systems Biology of Signal Transduction is seeking for the next possible date a

Postdoctoral Researcher in Cancer Proteomics

Reference number: 2025-0068

The division “Systems Biology of Signal Transduction”, headed by Prof. Dr. Ursula Klingmüller, combines cutting-edge experimental approaches with computational modelling to unravel molecular mechanisms regulating cell communication and cell decisions, as a failure of these control mechanisms contributes to tumor development.
In close cooperation with our mathematical modelling partners and the clinical partners, we are developing cutting edge mass spectrometry approaches for clinical proteomics and combine data science with dynamic pathway modeling. The key areas of medical interest are processes determining the prevention and development of cancer in the lung and the liver.
To complement our dynamic team, we are looking for a postdoctoral researcher in cancer proteomics.

Your Tasks

Develop and optimize targeted and phosphoproteomics workflows to analyze signal transduction pathways in clinical plasma and tissue samples.
Establish high-throughput, standardized mass spectrometry-based methods for large-scale clinical sample analysis and biomarker discovery.
Integrate mechanistic mathematical modeling with proteomics data to uncover biologically relevant insights in cancer research.
Analyze complex mass spectrometry datasets using advanced computational and statistical approaches, collaborating closely with clinicians, bioinformaticians, and computational biologists.
Publish research in high-impact journals, present at conferences, contribute to grant applications, and mentor PhD students and junior researchers.

Your Profile

PhD in biochemistry, molecular biology, bioinformatics, systems biology, or a related field
Strong expertise in mass spectrometry-based proteomics, including targeted proteomics and phosphoproteomics
Experience in quantitative data analysis and statistical methods for high-throughput omics datasets
Familiarity with mechanistic mathematical modeling and computational tools for systems biology is of advantage
Strong publication record in relevant peer-reviewed journals and excellent interdisciplinary communication skills and proficiency in English

We Offer

Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
Remuneration according to TV-L incl. company pension scheme and capital-forming benefits
30 days of vacation per year
Flexible working hours
Possibility of part-time work
Family-friendly working environment
Sustainable travel to work: subsidized Germany job ticket
Our Corporate Health Management Program offers a holistic approach to your well-being
Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents

Contact

Prof. Dr. Ursula Klingmüller
Phone: +49 6221 42-4481

The position is initially limited to 2 years with the possibility of prolongation.

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Applications by e-mail cannot be accepted.
Please also note that we cannot return applications submitted by post.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, personal identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

Deutsches Krebsforschungszentrum | Im Neuenheimer Feld 280 | 69120 Heidelberg | www.dkfz.de

Jetzt bewerben

Vollzeit , Befristete Anstellung

Postdoc

Aktualisiert am 13.03.2025

Bitte beziehe dich bei deiner Bewerbung auf jobvector und verwende die folgende Referenznummer: 2025-0068