PhD Student (gn*) Biology, Biochemistry, Biomedicine, Experimental Medicine, Medicine
Münster, Nordrhein-Westfalen
PhD Student (gn*) Biology, Biochemistry, Biomedicine, Experimental Medicine, Medicine
Fixed-term until 31.12.2028 | Part-time with 65% (25 hours/week) | Salary according to salary group 13 TV-L | Job ID: 10152
We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.
To meet our high standards every day, we are looking forward to your scientific expertise in the Department of Anesthesiology, Intensive Care and Pain Therapy - ideally with you on board!
Our group studies the mechanisms of immune cell activation and recruitment of inflammation in various mouse models. In detail, this project addresses immunoregulatory, metabolic and organ-specific as well as systemic molecular changes during acute kidney injury and organ dysfunction.
As a part of the collaborative network (CRC1450 inSight), this project provides an exciting and dynamic research environment with a broad range of state-of-the-art technologies from various departments, with excellent opportunities for networking and collaborations.
Your Tasks
- Intravital microscopy studies in mice to study live tissue dynamics
- Flow cytometry and sorting of specific cell populations
- Perform metabolic assays, including assessment of mitochondrial respiration and glycolysis
- Conduct scRNAseq/bulkRNAseq for gene expression analysis
- Use spatial transcriptomics for studying gene expression in tissue context
- Carry out immunofluorescence microscopy to visualize cellular components
- Investigate protein-protein interactions
- Perform retroviral transfection of bone marrow cells
- Generate bone marrow chimeras for studying hematopoiesis
What we expect:
- Master's degree in biology, biochemistry, biomedicine, experimental medicine, medicine or other related subjects/life sciences
- Strong knowledge in molecular biology, biochemical and immunological techniques such as western blot, flow cytometry, cell culture, ELISA, metabolomics or RNAseq/transcriptomics approaches
- Ideally you have obtained knowledge and skills in bioinformatics analyses, including 10x pipelines and omics analyses, R/Python
- Experience in working with mice or imaging techniques is not essential, but would be beneficial
- Independent, reliable and structured way of working with a good sense of quality is essential
- Motivation, flexibility, good self-organization and team working abilities
- Ability to analyse and critically reflect scientific data
- Determination, profound knowledge and resilience to successfully complete the project and advance the scientific field
- Good written and spoken English language skills
- Interest in doing and understanding science
- Willingness to organize and prioritize work
What we offer:
- Career development in a multidisciplinary and committed research team, mentorship, room for your ideas, problem solving, and teamwork will be strongly promoted
- Work-life balance - Münster is one of the cities with the best quality of life
- Modern infrastructure, international and collaborative research environment
BENEFITS
- Exciting Projects
- Professional Development and Training
- Interdisciplinary Collaboration
- Part of Research Innovation
- Additional Benefits
For inquiries, please contact Dr. Andreas Margraf, T 0251 83-46838
We are looking forward to your online application by 05.02.2025.
Formal applications should include:
- A cover letter with a brief statement of research experience, research interests, research techniques and career goals
- A CV with education certificates and grades
- Contact information of two possible referees (address, phone number and email)
The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.
Universitätsklinikum Münster
Albert-Schweitzer-Campus 1, Gebäude D5
48149 Münster
www.ukm.de
Albert-Schweitzer-Campus 1
48149 Münster
Nordrhein-Westfalen
Deutschland
- Hamm
- Osnabrück
- Herne
- Recklinghausen
- Marl
- Lünen
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