Headerbild Universitätsklinikum Tübingen

About us

The University Hospital of Tübingen is a leading center of German university medicine. Every year, around 75,000 inpatients and around 380,000 outpatients are treated. With around 10,600 employees, it is the largest employer in the region. The quality of patient care is certified with the KTQ seal of approval.

About the Lab

The Lab of Translational Microbiome Research (Head: C. Stein-Thoeringer) at the University of Tübingen, part of the Cluster of Excellence “Controlling Microbes to Fight Infections- (CMFI), studies the cross-talk between gut microbes, pathogens, the immune system and environmental factors in cancer development, therapy and infections. Our goal is to understand how individual bacteria, microbial consortia and microbial perturbations (e.g., through diet or antibiotics) influence inflammatory responses and metabolic disturbances to drive carcinogenesis and metastasis in preclinical models. We also investigate how cancer therapies interact with the gut microbiome in patients and mouse models, exploring causal relationships through direct host-microbe interactions or microbial metabolites. We combine advanced wet-lab and bioinformatics approaches, including culture-omics, high-resolution metagenome sequencing, and multi-omics profiling of the host-s immune system and metabolome. Causal microbe-host interactions are further examined using (gnotobiotic) mouse models. On the translational side, we conduct clinical studies to analyze patient microbiomes, disease associations, and environmental influences, as well as microbiome-based interventions to improve patient outcomes.

This position focuses on experimental work validating host-microbiome interactions to explore the microbiome-s role in CAR-T cell therapy against. It provides an excellent opportunity to gain experience in translational microbiome research and build a strong scientific profile for a career in academia, industry, or clinical research.

PostDoc (f/m/d)

Medical University Clinic, Lab of Translational Microbiome Research / M3, index number 5982

Full-time: 100 % | Limited: 2 years | Start of work: as soon as possible | Application deadline: 21.04.2025

Key Responsibilies

Investigate the mechanistic role of the microbiome in CAR-T cell therapy and cancer
Isolate and characterize disease-associated microbial strains
Analyze microbial metabolism and immune modulation
Develop and optimize in vitro models to study microbe-immune cell interactions
Contribute to biomarker discovery and microbiome-based therapies
Collaborate with clinical partners Supervise students and research assistants
Contribute to grant applications and high-impact publications
Present findings at national and international conferences

Requirements / Qualifications

PhD (or equivalent) in microbiology, biology, immunology or a related field
Strong background in research on host-microbe interactions, immunology, microbiology
Experience in classical and molecular microbiology techniques, immunology and mouse work
Experience with immunological assays (FACS etc.) and cell lines
Strong publication record and demonstrated research productivity (first-author publications in peer-reviewed journals)
Excellent communication skills and proficiency in English (written and spoken)
High attention to detail, strong analytical skills and excellent time management
Self-motivated, well organized and able to work independently and collaborative

Benefits

Working in the diverse environment of a modern university hospital, which, in addition to healthcare, also focuses on medical research and teaching
Future-proof job and location as well as attractive remuneration including company pension scheme (VBL) with the most flexible working hours possible
Subsidy for tickets for local public transport and attractive discounts on our offer platforms for employees
Structured onboarding phase, hospital's own academy to expand technical, social and methodological skills
Health care through a wide range of sports activities

Contact for questions

Frau Dr. Stefanie Bunk
email
email

Online Application to
Herr Prof. Christoph Stein-Thoeringer
Index number: 5982
Including CV and cover letter

Application deadline: 21.04.2025

We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States), severely handicapped persons with equal qualifications are given preferential consideration. Interview expenses are not covered. Please note the applicable vaccination regulations.

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Postdoc

Aktualisiert am 26.03.2025

Bitte beziehe dich bei deiner Bewerbung auf jobvector und verwende die folgende Referenznummer: 5982