The Department of Dermatology at the University Hospital Düsseldorf is a globally recognized Center for Advanced Research in skin diseases. Our state-of-the-art program encompasses a variety of projects including the study of the molecular drivers of chronic inflammatory skin diseases, the neuro-immune communication and microbe-host interactions. We use state-of-the-art OMICs techniques and in-house bioinformatics combined with in vitro- and in vivo-models with the goal to translate basic science findings into clinical use.
Department: Department of Dermatology
Location: University Hospital Düsseldorf, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany
PhD Student
The employment is initially limited for a period of three years. In accordance with §2 Abs. 2 of the Act of Academic Fixed-Term Contract (Wissenschaftszeitvertragsgesetz - WissZeitVG), the position is limited to the realization of an intramuraly funded project.
Overview of active projects:
- DFG-RU2690 PruSEARCH: Unraveling pruritus pathways in chronic inflammatory skin diseases
- EU-BIOMAP (No 821511): Investigating cutaneous microbe-host interactions
- DFG-RU5489 Investigating the ambiguous ways of the aryl hydrocarbon receptor (AHR) signalling in skin diseases: The AHR as a target for microbe-host interaction
- EU-SKINDEV (Skin microbial devices; No 101098826): Designing genetically modified probiotic organisms to treat atopic skin inflammation
- DFG-HO 2092/8-1: Epidermal growth factor signaling controls skin barrier function and the cutaneous microbiome
- FOKO 2023-40: Precision-cut skin slices as a novel tool for precision medicine in patients with refractory/therapy-resistant psoriatic inflammation
Position Summary:
We are seeking a highly motivated PhD student to join our dynamic team. The successful candidate will be involved in cutting-edge research, contributing significantly to our understanding and treatment of inflammatory skin diseases, by engaging in one of the active projects. This is an exceptional opportunity for a student passionate about dermatological research and looking to make a substantial impact in the field.
Key Responsibilities:
- Conducting innovative research in line with the abovementioned projects.
- Data collection, analysis, and interpretation using various OMICSs techniques.
- Perform in vitro and in vivo experiments.
- Collaborating with a multidisciplinary team of researchers and clinicians.
- Contributing to scientific papers and presenting findings at conferences.
- Actively participating in departmental seminars, workshops, and training sessions.
Qualifications:
- Master’s degree in (Medical) Biology, Biomedical Sciences, Bioinformatics, or a related field.
- Strong background in molecular and cellular biology or immunology.
- Knowledge about, or previous experience with cutaneous microbiome is an advantage.
- Excellent analytical, organizational, and communication skills.
We Offer:
- A vibrant, collaborative, and international research environment.
- Supervision and mentorship by leading experts in (experimental) dermatology.
- Opportunity to learn and utilize state-of-the-art technologies in cutting-edge facilities including scRNAseq, spatial transcriptomics, imaging mass cytometry, codex platform, metagenomics.
- In vitro-skin models, ex vivo-skin organ culture and precision cut skin slices
- Opportunities for academic and professional development.
- Funding support for the duration of the PhD program.
- In-house/group bioinformatic expertise and tutoring
- Interdisciplinary collaborations with Rheumatology, Microbiology, Immunology
Salary range: income is of the TV-L E13 pay grade group (38,5 weekly working hours).
Application Process: Interested candidates should submit a detailed CV, a motivation letter, academic transcripts, and contact details of two references.
Application Deadline: September 1st, 2024
Contact Information:
Univ.-Prof. Dr. Bernhard Homey
Dept. of Dermatology, University Hospital Düsseldorf, Medical Faculty, Heinrich-Heine-University Düsseldorf
email
The University Hospital Düsseldorf is an equal opportunity employer and strongly encourages applications from all qualified candidates.
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Universitätsklinikum Düsseldorf
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