We are one of the youngest universities in Germany and think in terms of possibilities, not limitations. In the heart of the Ruhrregion, we develop ideas of the future at our 11 faculties. We are strong in research and teaching, live diversity, support potential and are highly committed to an educational equality that has earned this name.
The University Hospital Essen offers first class medical services in the Ruhr metropolis. Every year, 225.000 patients are treated in 30 clinics, 27 institutes and specialized centers. The over 8.000 employees offer medical care with state-of-the art diagnostics and therapies, which meet highest international standards. Patient care is connected with basic and translational research at an international competitive level.
PhD Position (m/f/d)
Activities and responsibilities
The advertised position is located at the Department for Radiotherapy (principle investigator(s): Prof. Dr. Martin Stuschke. The project is linked to the focus area Lung Cancer of the GRK.
The PhD project of Prof. Stuschke and Dr. Sak will study the effect of epigenetic modulation of chromatin on the sensitivity of lung cancer cell lines to cisplatin or irradiation as defined in the project. The role of miRNAs with reported function in regulating key chromatin remodellers and their effect on the DNA damage response and radiosensitivity in a panel of molecularly defined cell lines representing clinically relevant NSCLC subtypes.
The GRK 2762 on “Heterogeneity, plasticity and dynamic in cancer cell, tumor and normal tissue responses to cancer radiotherapy” offers outstanding internationally-oriented interdisciplinary scientific research and training opportunities for graduates of experimental or computational life sciences and (bio)medicine with interest in basic and translational cancer research and computational biology (
http://www.uni-due.de/med/forschung/grk2762/index.shtml)
Qualification profile
Qualification profile - Talented and enthusiastic candidates with high interest in the research topic of GRK 2762
- Strong Diploma/Master degree in Cell or Molecular Biology, Biochemistry, Radiation Biology, Experimental Diploma/Master degree Medicine, Computational Biology or related fields
- High motivation and commitment for active cross-disciplinary collaboration
- Abilities for problem-solving and independent work
- Work with laboratory animals may be obligatory (depending on the project)
- Fluent in spoken and written English (knowledge of German is not a requirement)
We offer
We offer - Opportunity to conduct high-level interdisciplinary research projects
- Stimulating interdisciplinary and internationally-oriented academic environment
- Innovative cross-disciplinary scientific training for PhD and MD students at the interface between radiation biology and oncology, precision medicine, and computational biology
- Training in transferable academic and soft skills
- Funding for active participation in workshops and conferences and international visits to collaboration partners
- Regular supervision and mentoring
- Excellent career opportunities
Applications
Interested candidates should fill in the application form available at http://www.uni-due.de/med/forschung/grk2762/index.shtml and send it together with a curriculum vitae, a copy of all university degrees and other certificates (e.g., on English language skills, FELASA B qualification) and the indication of two referees (University professors) in a single pdf-file. Application GRK 2762/Project L4 to email or email or to Universitätsklinikum Essen, Personaldezernat, Hufelandstraße 55, 45147 Essen, Germany.
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